DAP-seq is fast, inexpensive, easily scaled method enabling high-throughput generation of cistrome and epicistrome maps for any organism.
The small green trays of plants in this Salk Institute greenhouse are far more captivating to these researchers than the ocean view. Carol Huang reaches out for a tray. “Can we get the seeds?” she asks as she examines the flat of maturing Arabidopsis plants. “These are too young,“ Huang says. Huang and fellow Salk […]
Infertile couples might be able to greatly boost their chances of having a baby by using the genetic discards of egg cells, researchers from the Salk Institute and Oregon Health and Science University said in a new study. Moreover, the technology could be used to prevent diseases of mitochondria — the cell’s energy factories — […]
An international team of scientists has sequenced the whole genomes and epigenomes of more than 1,000 Arabidopsis thaliana plants, sampled from geographically diverse locations. The collection of 1,001 genomes and 1,001 epigenomes not only illuminates new aspects of the plant’s evolutionary history, but also provides a comprehensive, species-wide picture of the interaction between genetic and […]
Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory-generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells. The tests found that no current protocols lead to truly naïve stem cells, but the guidelines […]
First day @latrobe AgriBio! Incredible modern building and acres of growth space. My office needs some plants tho. pic.twitter.com/kb1AcR14lw
LA JOLLA—A new technique developed by Salk Institute scientists for rapidly mapping regions of DNA targeted by regulatory proteins could give scientists insight into what makes some plants drought tolerant or disease resistant, among other traits. Revealing this landscape of protein-binding zones on DNA, collectively dubbed the “cistrome,” shows how plants control where and when […]
Agricultural grafting dates back nearly 3,000 years. By trial and error, people from ancient China to ancient Greece realized that joining a cut branch from one plant onto the stalk of another could improve the quality of crops. Now, researchers at the Salk Institute and Cambridge University have used this ancient practice, combined with modern […]