Lab News

Chongyuan Luo in Nature Communications

Congratulations Chongyuan Luo on Nature Communications publication describing snmC-seq2 – terrific improvements to single cell methylome profiling method!

Congrats Bobby!

Bobby Henley received an BRAIN Initiative Fellows: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship.

Congrats Shelly!

Shelly submitted her thesis on August 31! Congrats Shelly – moving on to postdoc at UW!

Ecker Lab featured in Science News

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*From sciencenews.org In a landmark event more than a decade ago, geneticists unveiled the human genetic instruction book. This year, the book was turned into a movie adaptation in 3-D: Researchers cataloged how chemical (more…)

Shelly Trigg’s work lands on the cover of Nature Methods

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Shelly Trigg’s work lands on the cover of Nature Methods. Congrats Shelly et al! (more…)

Mapping genome-wide transcription-factor binding sites using DAP-seq

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DAP-seq is fast, inexpensive, easily scaled method enabling high-throughput generation of cistrome and epicistrome maps for any organism. (more…)

Arabidopsis Research Roundup: January 29th

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This weeks Arabidopsis Research Roundup features a paper from David Baulcombe and Joe Ecker that further deciphers mechanisms of RNA silencing and is kindly discussed by postdoc Mat Lewsey in a short audio description. Elsewhere there are three studies that include researchers from CPIB in Nottingham. (more…)

Ecker Lab featured in Popular Science

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*From popsci.com June marked the release of the first map of the human epigenome: the chemical markers that tell your DNA what to express when. “Think of the genome as the hardware in your computer and the epigenome as the software,” says Joseph Ecker, director of the (more…)

Ecker Lab featured in Discover Magazine

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*From discovermagazine.com In the 12 years since the Human Genome Project was completed, biologists have linked more than a thousand regions of the genome to disease. “But in most cases, we don’t actually know how they function,” says Manolis Kellis, a computational biologist at Massachusetts Institute of Technology. Enter the epigenome. (more…)

Grafted plants’ genomes can communicate with each other

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Agricultural grafting dates back nearly 3,000 years. By trial and error, people from ancient China to ancient Greece realized that joining a cut branch from one plant onto the stalk of another could improve the quality of crops. (more…)

Salk researchers chart landscape of genetic and epigenetic regulation in plants

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LA JOLLA—A new technique developed by Salk Institute scientists for rapidly mapping regions of DNA targeted by regulatory proteins could give scientists insight into what makes some plants drought tolerant or disease resistant, among other traits. (more…)

Congratulations Ecker lab alumni Mat Lewsey on launching his new group down under!

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First day @latrobe AgriBio! Incredible modern building and acres of growth space. My office needs some plants tho. pic.twitter.com/kb1AcR14lw

Gauging stem cells for regenerative medicine

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Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory-generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells. The tests found that no current protocols lead to truly naïve stem cells, (more…)

Extensive Variation Revealed in 1001 Genomes and Epigenomes of Arabidopsis

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An international team of scientists has sequenced the whole genomes and epigenomes of more than 1,000 Arabidopsis thaliana plants, sampled from geographically diverse locations. The collection of 1,001 genomes and 1,001 epigenomes not only illuminates new aspects of the plant’s evolutionary history (more…)

Fertility success may get boost from new research

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Infertile couples might be able to greatly boost their chances of having a baby by using the genetic discards of egg cells, researchers from the Salk Institute and Oregon Health and Science University said in a new study. (more…)

Salk Researchers Say Plant May Hold Key To Drought Resistance

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The small green trays of plants in this Salk Institute greenhouse are far more captivating to these researchers than the ocean view. Carol Huang reaches out for a tray. (more…)

New kinds of brain cells discovered by Salk, UCSD scientists

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Scientists from the Salk Institute and University of California San Diego report identifying a number of previously unknown types of human brain cells. They’ve also discovered genetic switches that make these neurons. (more…)

Systemic silencing: Mobile sRNA stabilizes genomes

Transcriptional gene silencing is a pivotal mechanism for regulating gene expression and genome stability. In Arabidopsis, combined analyses of small RNAs (sRNAs) and DNA methylation reveals that mobile 24-nt sRNAs are involved in reinforcing genome-wide silencing of transposons through DNA methylation. (more…)